Piperazine: uses, dosing, side effects & brands
Piperazine is a medicine sold in the U.S. under 3 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Tablet · Syrup
- Sold as
- 3 products — Antepar, Bryrel and Multifuge
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Every piperazine product we track (3)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | No data | — | View → | |
| 2 | 70/100 | Prescription | Syrup | No data | — | View → | |
| 3 | Not yet rated | Prescription | Syrup | No data | — | View → |
What people report to the FDA about piperazine
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 6 reports naming piperazine, and the FDA flagged 100% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- hereditary angioedema3 reports
- malaise3 reports
- poor venous access3 reports
- abdominal distension1 reports
- abdominal pain1 reports
- ascites1 reports
- constipation1 reports
- decreased appetite1 reports
Read these as a signal, not a rate. A report does not mean piperazine caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 27, 2026.
Related calculators
Frequently asked questions
Can you take piperazine with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run piperazine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is piperazine sold under?
We track 3 piperazine-containing products in the U.S.: Antepar, Bryrel and Multifuge. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does piperazine come in?
Across the brands we track, piperazine is currently marketed as tablet and syrup, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic piperazine?
We do not currently list a generic-labelled piperazine product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Piperazine: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/piperazine
- MLA
- “Piperazine: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/piperazine.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for piperazine on DailyMed (NIH) ↗.