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Phosphatidylserine: uses, dosing, side effects & brands

Phosphatidylserine is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesUpdated Jul 24, 2026How we research

Key facts

Sold as
Phosphatidylserine
Generic available?
Yes

Every phosphatidylserine product we track (1)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Only one: Phosphatidylserine.

What people report to the FDA about phosphatidylserine

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 55 reports naming phosphatidylserine, and the FDA flagged 64% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • suicidal ideation9 reports
  • headache8 reports
  • depression7 reports
  • diarrhoea7 reports
  • fatigue7 reports
  • anxiety6 reports
  • asthenia4 reports
  • confusional state4 reports

Read these as a signal, not a rate. A report does not mean phosphatidylserine caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.

Source: openFDA drug/event (FAERS), retrieved July 27, 2026.

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Frequently asked questions

What is Phosphatidylserine?

Phosphatidylserine is a dietary supplement.

Can you take phosphatidylserine with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run phosphatidylserine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Is there a generic phosphatidylserine?

Yes. Our catalog lists 1 generic phosphatidylserine product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Cite this page
APA
pharmaranks. (2026, July 24). Phosphatidylserine: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/phosphatidylserine
MLA
“Phosphatidylserine: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/phosphatidylserine.

We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.

Read the full FDA label for phosphatidylserine on DailyMed (NIH) ↗.