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Naphazoline: uses, dosing, side effects & brands

Naphazoline is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesUpdated Jul 24, 2026How we research

Key facts

Available as
Drops
Sold as
Naphazoline Hydrochloride
Prescription?
Prescription only
Generic available?
Yes

Every naphazoline product we track (1)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Only one: Naphazoline Hydrochloride.

Combination products containing naphazoline

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

Naphazoline recalls

From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.

What people report to the FDA about naphazoline

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 403 reports naming naphazoline, and the FDA flagged 67% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • fatigue99 reports
  • headache90 reports
  • rash83 reports
  • inappropriate schedule of product administration82 reports
  • pyrexia80 reports
  • weight decreased80 reports
  • pain in extremity79 reports
  • covid-1978 reports

Read these as a signal, not a rate. A report does not mean naphazoline caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.

Source: openFDA drug/event (FAERS), retrieved July 25, 2026.

Related calculators

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Frequently asked questions

Can you take naphazoline with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run naphazoline against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What forms does naphazoline come in?

Across the brands we track, naphazoline is currently marketed as drops, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic naphazoline?

Yes. Our catalog lists 1 generic naphazoline product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Has naphazoline been recalled?

The FDA's Enforcement database lists 4 recall records whose product description mentions naphazoline. The most recent: Rohto Cooling Eye Drops Cool Relief (naphazoline hydrochloride 0.012% (Jul 14, 2026). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

Cite this page
APA
pharmaranks. (2026, July 24). Naphazoline: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/naphazoline
MLA
“Naphazoline: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/naphazoline.

We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.

Read the full FDA label for naphazoline on DailyMed (NIH) ↗.