Ingenol Mebutate: uses, dosing, side effects & brands
Ingenol Mebutate is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Topical
- Sold as
- Picato
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Every ingenol mebutate product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Picato.
What people report to the FDA about ingenol mebutate
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 221 reports naming ingenol mebutate, and the FDA flagged 12% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- application site erythema98 reports
- application site vesicles72 reports
- application site pain68 reports
- drug administered at inappropriate site59 reports
- application site exfoliation46 reports
- application site scab30 reports
- incorrect drug administration duration29 reports
- application site swelling28 reports
Read these as a signal, not a rate. A report does not mean ingenol mebutate caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 25, 2026.
Related calculators
Frequently asked questions
Can you take ingenol mebutate with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run ingenol mebutate against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does ingenol mebutate come in?
Across the brands we track, ingenol mebutate is currently marketed as topical, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic ingenol mebutate?
We do not currently list a generic-labelled ingenol mebutate product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Ingenol Mebutate: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/ingenol-mebutate
- MLA
- “Ingenol Mebutate: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/ingenol-mebutate.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for ingenol mebutate on DailyMed (NIH) ↗.