Doxylamine: uses, dosing, side effects & brands

Key facts

Frequently asked questions

What is doxylamine?

Use • helps to reduce difficulty in falling asleep

What kind of drug is doxylamine?

The FDA classifies doxylamine as an antihistamine. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Can you take doxylamine with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run doxylamine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is doxylamine sold under?

We track 2 doxylamine-containing products in the U.S.: Unisom and Decapryn. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does doxylamine come in?

Across the brands we track, doxylamine is currently marketed as capsule and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic doxylamine?

We do not currently list a generic-labelled doxylamine product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.

Has doxylamine been recalled?

The FDA's Enforcement database lists 1 recall record whose product description mentions doxylamine. The most recent: Kirkland Severe Cold & Flu Plus Congestion: Day (Nov 14, 2024). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.