Diflunisal: uses, dosing, side effects & brands
Diflunisal is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Tablet
- Sold as
- Dolobid
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
- What the pharmacy pays
- about $35 for a 30-count supply — not your price
Every diflunisal product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Dolobid.
What diflunisal pills look like
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
Can you crush or split diflunisal?
At least one diflunisalproduct is labelled to be swallowed whole — crushing an extended-release tablet releases the whole day’s dose at once. Which applies depends on the form you were given.
What each diflunisal label says about crushing, splitting and chewingHow long diflunisal keeps
No diflunisal label we read sets a separate limit for after opening, but they do specify how it must be stored — and the stability behind any date assumes those conditions.
Does diflunisal expire? The in-use limits and storage rules from its labelsDiflunisal and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for diflunisal: levels in milk, effects in breastfed infants, and the drugs it would consider insteadThe small amounts of diflunisal in milk do not appear to pose a serious risk to breastfeeding infants. However, a shorter-acting agent may be preferred, especially while nursing a newborn or preterm infant.
National Institute of Child Health and Human Development, record revised June 15, 2025. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about diflunisal
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 652 reports naming diflunisal, and the FDA flagged 60% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- nausea49 reports
- fatigue44 reports
- arthralgia34 reports
- fall32 reports
- headache31 reports
- diarrhoea30 reports
- platelet count decreased30 reports
- drug hypersensitivity27 reports
Read these as a signal, not a rate. A report does not mean diflunisal caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 25, 2026.
Related calculators
Frequently asked questions
Can you take diflunisal with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run diflunisal against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does diflunisal come in?
Across the brands we track, diflunisal is currently marketed as tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic diflunisal?
We do not currently list a generic-labelled diflunisal product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Diflunisal: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/diflunisal
- MLA
- “Diflunisal: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/diflunisal.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for diflunisal on DailyMed (NIH) ↗.