Daratumumab: uses, dosing, side effects & brands
Daratumumab is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Injectable
- Sold as
- Darzalex
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Every daratumumab product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Darzalex.
Combination products containing daratumumab
A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.
Can you crush or split daratumumab?
The daratumumab labels that address it permit crushing or splitting in the terms they state — quoted per product, because the instruction belongs to the form.
What each daratumumab label says about crushing, splitting and chewingDaratumumab and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for daratumumab: levels in milk, effects in breastfed infants, and the drugs it would consider insteadNo information is available on the clinical use of daratumumab during breastfeeding. Because daratumumab is a large protein molecule with a molecular weight of 148,000 Da, the amount in milk is likely to be very low. It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal. Waiting for at least 2 weeks postpartum to resume therapy may minimize transfer to the infant. However, daratumumab is administered with lenalidomide, pomalidomide, or thalidomide, three drugs that have no information on use in nursing mothers. For this reason, the manufacturer recommends that women receiving daratumumab should not breastfeed.
National Institute of Child Health and Human Development, record revised November 15, 2023. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about daratumumab
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 17,983 reports naming daratumumab, and the FDA flagged 94% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- plasma cell myeloma1,739 reports
- neutropenia1,203 reports
- pneumonia1,185 reports
- thrombocytopenia800 reports
- diarrhoea705 reports
- pyrexia690 reports
- fatigue671 reports
- anaemia657 reports
Read these as a signal, not a rate. A report does not mean daratumumab caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
Related calculators
Frequently asked questions
Can you take daratumumab with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run daratumumab against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does daratumumab come in?
Across the brands we track, daratumumab is currently marketed as injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic daratumumab?
We do not currently list a generic-labelled daratumumab product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Daratumumab: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/daratumumab
- MLA
- “Daratumumab: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/daratumumab.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for daratumumab on DailyMed (NIH) ↗.