Cyanocobalamin: uses, dosing, side effects & brands

How cyanocobalamin is dosed

From the FDA label for Redisol (application NDA006668). Other cyanocobalamin products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

Avoid using the intravenous route. Use of this product intravenously will result in almost all of the vitamin being lost in the urine. Pernicious Anemia Parenteral Vitamin B 12 is the recommended treatment and will be required for the remainder of the patient's life. The oral form is not dependable. A dose of 100 mcg daily for six or seven days should be administered by intramuscular or deep subcutaneous injection. If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every three to four days for another two to three weeks. By this time hematologic values should have become normal. This regimen should be followed by 100 mcg monthly for life. Folic acid should be administered concomitantly if needed. Patients with Normal Intestinal Absorption Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency. Chronic treatment should be with an oral B 12 preparation. If other vitamin deficiencies are present, they should be treated. Schilling Test The flushing dose is 1,000 mcg. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Cyanocobalamin side effects

Generalized Anaphylactic shock and death have been reported with administration of parenteral Vitamin B 12 (see WARNINGS ). Cardiovascular Pulmonary edema and congestive heart failure early in treatment; peripheral vascular thrombosis. Hematological Polycythemia vera. Gastrointestinal Mild transient diarrhea. Dermatological Itching; transitory exanthema. Miscellaneous Feeling of swelling of entire body.

Who shouldn’t take cyanocobalamin

Sensitivity to cobalt and/or Vitamin B 12 is a contraindication.

Every cyanocobalamin product we track (9)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

What cyanocobalamin pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Combination products containing cyanocobalamin

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

• Mvc Plus
• M.V.I. Adult
• M.V.I. Pediatric
• M.V.I.-12 Adult
• Vitaped
• Berocca Pn
• Depinar
• Dicopac Kit
• Infuvite Adult
• Infuvite Pediatric
• Infuvite Pediatric (Pharmacy Bulk Package)
• M.V.C. 9+3

Cyanocobalamin recalls

From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.

• Semaglutide-Glycine-Cyanocobalamin Injectable

  Lack of Assurance of Sterility

  PAYLESS COMPOUNDERS, LLC · Mar 6, 2026

• Semaglutide + Cyanocobalamin 0.44 mg + 0.25mg/0.5 mL Inj Sol

  Lack of Processing Controls.

  AEQUITA PHARMACY · Jul 18, 2025

• Semaglutide + Cyanocobalamin 2.67 mg + 0.25mg/0.5 mL Inj Sol

  Lack of Processing Controls.

  AEQUITA PHARMACY · Jul 18, 2025

• Semaglutide + Cyanocobalamin 0.88 mg + 0.25mg/0.5 mL Inj Sol

  Lack of Processing Controls.

  AEQUITA PHARMACY · Jul 18, 2025

• Semaglutide + Cyanocobalamin 0.22 mg + 0.25mg/0.5 ml Inj Sol

  Lack of Processing Controls.

  AEQUITA PHARMACY · Jul 18, 2025