Question 1

What is clobazam?

Accepted Answer

Table 4. Description Proprietary Name: ONFI ® Established Name: Clobazam Dosage Forms: Tablet and Oral Suspension Route of Administration: Oral Established Pharmacologic Class of Drug: Benzodiazepine Chemical Name: 7-Chloro-1-methyl-5-phenyl-1H-1,5 benzodiazepine-2,4( 3H,5H )-dione Structural Formula: Clobazam is a white or almost white, crystalline powder with a slightly bitter taste; is slightly soluble in water, sparingly soluble in ethanol, and freely soluble in methylene chloride. The melting range of clobazam is from 182ºC to 185ºC. The molecular formula is C 16 H 13 O 2 N 2 Cl and the molecular weight is 300.7. Each ONFI tablet contains 10 mg or 20 mg of clobazam. Tablets also contain as inactive ingredients: modified corn starch, lactose monohydrate, magnesium stearate, silicon dioxide, and talc. ONFI is also available for oral administration as an off-white suspension containing clobazam at a concentration of 2.5 mg/mL. Inactive ingredients include magnesium aluminum silicate, xanthan gum, citric acid monohydrate, disodium hydrogen phosphate dihydrate, simethicone emulsion, polysorbate 80, methylparaben, propylparaben, propylene glycol, sucralose, maltitol solution, berry flavor, purified water. onfi-01

Question 2

What kind of drug is clobazam?

Accepted Answer

The FDA classifies clobazam as a benzodiazepine. Benzodiazepines boost the brain's main calming chemical, GABA, by binding to the GABA-A receptor and making its chloride channel open more often. This quiets nerve activity, producing sedation, reduced anxiety, muscle relaxation, and protection against seizures. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Question 3

Can you take clobazam with other medicines?

Accepted Answer

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run clobazam against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Question 4

What brand names is clobazam sold under?

Accepted Answer

We track 3 clobazam-containing products in the U.S.: Clobazam, Onfi and Sympazan. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Question 5

What forms does clobazam come in?

Accepted Answer

Across the brands we track, clobazam is currently marketed as suspension, tablet and film, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Question 6

Is there a generic clobazam?

Accepted Answer

Yes. Our catalog lists 1 generic clobazam product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Question 7

Has clobazam been recalled?

Accepted Answer

The FDA's Enforcement database lists 3 recall records whose product description mentions clobazam. The most recent: Clobazam Tablets (Jan 7, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

#	Drug	Rating	Type	Form	Generic?	Typical price
1	Clobazam	Not yet rated	Prescription	Suspension	Generic	$8	View →
2	Onfi Boxed warning

Clobazam: uses, dosing, side effects & brands

Key facts

How clobazam is dosed

Clobazam side effects

Every clobazam product we track (3)

What clobazam pills look like

Clobazam recalls

Frequently asked questions

Who shouldn’t take clobazam

Clobazam drug interactions

Imprint	Strength	Colour	Shape	Maker
1;0	10 mg	white	oval	—
2;0	20 mg	white	oval	—
C;2	10 mg	white	oval	—
C;3	20 mg	white	oval	—
1;0	10 mg	white	oval	—
2;0	20 mg	white