Clemastine belongs to the benzhydryl ether group of antihistaminic compounds. The chemical name is (+)-(2 R )-2-[2-[[( R )- p -Chloro-α-methyl-α-phenylbenzyl]-oxy]ethyl]-1-methylpyrrolidine fumarate (1:1). C 21 H 26 C1NO∙C 4 H 4 O 4 M.W. 459.97 Each tablet for oral administration contains 2.68 mg of clemastine fumarate, USP. Inactive ingredients: colloidal silicon dioxide, corn starch, lactose monohydrate, povidone, pregelatinized starch and stearic acid. Chemical Structure

Can you take clemastine with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run clemastine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is clemastine sold under?

We track 3 clemastine-containing products in the U.S.: Tavist-1, Tavist and Clemastine Fumarate. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does clemastine come in?

Across the brands we track, clemastine is currently marketed as tablet and syrup, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic clemastine?

Yes. Our catalog lists 1 generic clemastine product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Clemastine: uses, dosing, side effects & brands

Clemastine is a medicine sold in the U.S. under 3 brand and generic names, for angioedema, perennial allergic rhinitis and urticaria. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesHow we research

Key facts

Treats: Angioedema, Perennial Allergic Rhinitis and Urticaria
Available as: Tablet · Syrup
Sold as: 3 products — Tavist-1, Tavist and Clemastine Fumarate
Prescription?: Prescription only
Generic available?: Yes
Typical price: about $5 for a 30-count supply

How clemastine is dosed

From the FDA label for Tavist-1 (application NDA020925). Other clemastine products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

Clemastine Fumarate Tablets 2.68 mg The maximum recommended dosage is one tablet three times daily. Many patients respond favorably to a single dose which may be repeated as required, but not to exceed three tablets daily.

Clemastine side effects

Transient drowsiness, the most common adverse reaction associated with clemastine fumarate, occurs relatively frequently and may require discontinuation of therapy in some instances. Antihistaminic Compounds It should be noted that the following reactions have occurred with one or more antihistamines and, therefore, should be kept in mind when prescribing drugs belonging to this class, including clemastine. The most frequent adverse reactions are italicized. General: Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of the mouth, nose, and throat. Cardiovascular System: Hypotension, headache, palpitations, tachycardia, extrasystoles. Hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis. Nervous System: Sedation, sleepiness, dizziness, disturbed coordination , fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesias, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, hysteria, neuritis, convulsions. GI System: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation. GU System: Urinary frequency, difficult urination, urinary retention, early menses. Respiratory System: Thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.

Who shouldn’t take clemastine

Usage in Nursing Mothers Because of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers. Usage in Lower Respiratory Disease Antihistamines should not be used to treat lower respiratory tract symptoms including asthma. Antihistamines are also contraindicated in the following conditions: Hypersensitivity to clemastine fumarate or other antihistamines of similar chemical structure. Monoamine oxidase inhibitor therapy (see Drug Interactions section).

Every clemastine product we track (3)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Clemastine products
#	Drug	Rating	Type	Form	Generic?	Typical price
1	Tavist-1	72/100	Prescription	Tablet	Generic	$5	View →
2	Tavist	68/100	Prescription	Syrup	Generic

What clemastine pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Clemastine pill imprints
Imprint	Strength	Colour	Shape	Maker
NH;268	2.68 mg	white	round	—
NH;268	2.68 mg	white	round	—

Combination products containing clemastine

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

Tavist Allergy/Sinus/Headache

Frequently asked questions

What is clemastine?: Clemastine belongs to the benzhydryl ether group of antihistaminic compounds. The chemical name is (+)-(2 R )-2-[2-[[( R )- p -Chloro-α-methyl-α-phenylbenzyl]-oxy]ethyl]-1-methylpyrrolidine fumarate (1:1). C 21 H 26 C1NO∙C 4 H 4 O 4 M.W. 459.97 Each tablet for oral administration contains 2.68 mg of clemastine fumarate, USP. Inactive ingredients: colloidal silicon dioxide, corn starch, lactose monohydrate, povidone, pregelatinized starch and stearic acid. Chemical Structure
Can you take clemastine with other medicines?: It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run clemastine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is clemastine sold under?: We track 3 clemastine-containing products in the U.S.: Tavist-1, Tavist and Clemastine Fumarate. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does clemastine come in?: Across the brands we track, clemastine is currently marketed as tablet and syrup, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic clemastine?: Yes. Our catalog lists 1 generic clemastine product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.