Cefoperazone: uses, dosing, side effects & brands
Cefoperazone is a medicine sold in the U.S. under 2 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Injectable
- Sold as
- 2 products — Cefobid and Cefobid in Plastic Container
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Every cefoperazone product we track (2)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 64/100 | Prescription | Injectable | No data | — | View → | |
| 2 | 64/100 | Prescription | Injectable | No data | — | View → |
Cefoperazone and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for cefoperazone: levels in milk, effects in breastfed infants, and the drugs it would consider insteadCefoperazone is no longer marketed in the United States. Limited information indicates cefoperazone produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Cefoperazone is acceptable in nursing mothers.
National Institute of Child Health and Human Development, record revised September 15, 2023. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about cefoperazone
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 1,713 reports naming cefoperazone, and the FDA flagged 98% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- platelet count decreased123 reports
- pyrexia113 reports
- pneumonia106 reports
- hepatic function abnormal85 reports
- coagulopathy76 reports
- anaemia68 reports
- rash67 reports
- diarrhoea66 reports
Read these as a signal, not a rate. A report does not mean cefoperazone caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 25, 2026.
Related calculators
Frequently asked questions
Can you take cefoperazone with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run cefoperazone against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is cefoperazone sold under?
We track 2 cefoperazone-containing products in the U.S.: Cefobid and Cefobid in Plastic Container. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does cefoperazone come in?
Across the brands we track, cefoperazone is currently marketed as injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic cefoperazone?
We do not currently list a generic-labelled cefoperazone product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Cefoperazone: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/cefoperazone
- MLA
- “Cefoperazone: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/cefoperazone.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for cefoperazone on DailyMed (NIH) ↗.