Amoxicillin dosage
This is a reference summary of amoxicillin dosing taken directly from the FDA-approved label, not a prescription. Amoxicillin is prescription-only, and the right dose depends on which infection you have, how severe it is, a child's body weight, and kidney function. Every number below is quoted from the label so you can compare it against what you were prescribed; your prescriber selects the exact regimen for your diagnosis.
This is reference, not a dosing instruction. Amoxicillinis prescription-only and the dose is individualized and titrated by a prescriber to your condition, response, kidney/liver function and other medicines. The figures below are the FDA label’s — do not start, change or stop a dose based on this page.
Approved for: A penicillin-class antibiotic for bacterial infections of the ear, nose, and throat; genitourinary tract; skin and skin structure; and lower respiratory tract caused by susceptible organisms, plus Helicobacter pylori eradication in combination with clarithromycin and lansoprazole. Per the FDA label, amoxicillin and other antibacterial drugs 'do not treat viral infections (e.g., the common cold).'
Available as: Capsules 250 mg and 500 mg; tablets 500 mg and 875 mg; chewable tablets 125 mg and 250 mg; powder for oral suspension 200 mg/5 mL, 250 mg/5 mL, and 400 mg/5 mL.
| Use | What the label says |
|---|---|
| Adults - mild/moderate | For ear/nose/throat, genitourinary, and skin/skin-structure infections, the FDA label gives '500 mg every 12 hours or 250 mg every 8 hours' for mild-to-moderate infections. The two schedules deliver a similar daily total; the prescriber chooses based on the infection and convenience. |
| Adults - severe | For severe ear/nose/throat, GU, or skin infections - and for all lower respiratory tract infections regardless of severity - the label gives '875 mg every 12 hours or 500 mg every 8 hours.' Separately, H. pylori regimens use 1 gram of amoxicillin twice daily (with clarithromycin and lansoprazole) or three times daily (with lansoprazole) for 14 days. |
| Children (weight-based) | Pediatric patients over 3 months: mild/moderate infections '25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours'; severe infections and lower respiratory tract infections '45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours.' 'Children weighing 40 kg or more should be dosed according to the adult recommendations.' For neonates and infants 12 weeks (3 months) or younger, 'the recommended upper dose of amoxicillin... is 30 mg/kg/day divided every 12 hours.' |
Maximum dose
The label sets no single universal ceiling; dosing is capped by indication and body weight. The highest routine adult regimen is 875 mg every 12 hours (about 1,750 mg/day) or 500 mg every 8 hours (1,500 mg/day); H. pylori regimens use 1 gram (1,000 mg) per dose. Pediatric dosing tops out at 45 mg/kg/day for severe or lower-respiratory infections, and neonates/infants 12 weeks or younger should not exceed 30 mg/kg/day divided every 12 hours.
Dose adjustments
Dosage adjustment 'is usually required in patients with severe renal impairment (GFR <30 mL/min).' The label states: 'Severely impaired patients with a glomerular filtration rate <30 mL/min should not receive a 875 mg dose.' GFR 10 to 30 mL/min: '500 mg or 250 mg every 12 hours, depending on the severity of the infection.' GFR less than 10 mL/min: '500 mg or 250 mg every 24 hours.' Hemodialysis patients: '500 mg or 250 mg every 24 hours,' plus an additional dose both during and at the end of dialysis. No dosing recommendations are established for pediatric patients with renal impairment.
Dosing safety — read before you rely on any number
Amoxicillin treats bacterial infections only - the FDA label states antibacterial drugs 'do not treat viral infections (e.g., the common cold),' so it will not help a cold or the flu. Finish the full course: 'Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment, and (2) increase the likelihood that bacteria will develop resistance.' Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have occurred with penicillins - do not take amoxicillin if you are allergic to penicillin, and seek emergency care for rash, swelling, or trouble breathing. For strep throat/tonsillitis, 'it is recommended that there be at least 10 days' treatment... to prevent the occurrence of acute rheumatic fever.'
Bottom line
Treat this as a reference, not a prescription. The right amoxicillin regimen is set by the specific infection, its severity, a child's weight, and kidney function - the prescriber matches the schedule (every 8 vs every 12 hours) and the strength to your diagnosis. Take it exactly as directed and finish the entire course even if you feel better.
Frequently asked questions
What is the amoxicillin dosage for adults?
Per the FDA label, mild-to-moderate ear/nose/throat, urinary, or skin infections are treated with '500 mg every 12 hours or 250 mg every 8 hours.' Severe infections and all lower respiratory tract infections use '875 mg every 12 hours or 500 mg every 8 hours.' The prescriber picks the schedule based on the infection.
What is the amoxicillin dosage for children by weight?
For children over 3 months, the label uses weight-based dosing: mild/moderate infections at '25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours,' and severe or lower-respiratory infections at '45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours.' Children 40 kg or more are dosed as adults, and infants 3 months or younger should not exceed 30 mg/kg/day divided every 12 hours.
How many days do you take amoxicillin?
It depends on the infection - MedlinePlus notes 'the length of your treatment depends on the type of infection that you have,' and advises taking it 'until you finish the prescription, even if you feel better.' For strep throat/tonsillitis, the FDA label recommends 'at least 10 days' treatment' to prevent rheumatic fever. Never stop early just because symptoms improve.
Amoxicillin 500 mg - how often?
A 500 mg dose is taken either every 8 hours or every 12 hours depending on the regimen. The label uses '500 mg every 8 hours' for severe infections and lower respiratory tract infections, and '500 mg every 12 hours' for mild-to-moderate infections. Take doses at evenly spaced times, with or without food.
Can you take too much amoxicillin?
Yes - never exceed the prescribed dose. The highest routine adult regimen on the label is 875 mg every 12 hours; taking more does not work faster and raises the risk of side effects such as nausea, diarrhea, and crystalluria. People with reduced kidney function need lower doses (see renal adjustments). If an overdose is suspected, contact Poison Control (1-800-222-1222) or seek emergency care.
What's the amoxicillin dose for a tooth infection, strep throat, or UTI?
Strep throat and urinary tract infections fall under the label's ear/nose/throat and genitourinary categories - typically '500 mg every 12 hours or 250 mg every 8 hours' (severe cases '875 mg every 12 hours or 500 mg every 8 hours'), with strep needing at least 10 days. Dental (tooth) infections are not a specific FDA-labeled amoxicillin indication; dentists prescribe it based on dental-society guidance, commonly 500 mg every 8 hours. In every case the prescriber matches the regimen to the diagnosis - use this only as a reference.
How long does it take for amoxicillin to work?
Once amoxicillin starts fighting a susceptible bacterial infection, many people notice symptoms easing within the first few days of treatment - less fever, less pain, more energy. Feeling better, though, is not the same as being cured: the bacteria are being knocked down but are not all gone. MedlinePlus is explicit that you should 'Take amoxicillin until you finish the prescription, even if you feel better,' because 'If you stop taking amoxicillin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.' If you are not starting to improve after a few days - or you get worse at any point - do not just keep waiting: MedlinePlus advises, 'If your symptoms do not improve or get worse, call your doctor.' Some infections also carry their own minimum: for strep throat, the FDA label calls for at least 10 days of treatment to help prevent rheumatic fever, regardless of how quickly you feel well.
Sources
- FDA Prescribing Information - Amoxicillin Capsules (DailyMed) ↗
- FDA Prescribing Information - Amoxicillin Tablets 500/875 mg (DailyMed) ↗
- Amoxicillin - MedlinePlus Drug Information (U.S. National Library of Medicine) ↗
- CDC - Antibiotic Prescribing and Use (antibiotics don't work on viruses; take exactly as prescribed) ↗
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Doses are transcribed from the FDA-approved label and are general reference information, not medical advice or a personal dose. Only a prescriber can set or change your dose. If you think you took too much, contact Poison Control (1-800-222-1222) or 911.