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Best treatments for bacterial skin diseases

6 products may treat bacterial skin diseases, spanning FDA drug classes such as oxazolidinone antibacterial, aminoglycoside antibacterial, lipopeptide antibacterial. The current highest-rated option is sivextro. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 6 drugs we list for bacterial skin diseases, 4 are available as lower-cost generics, spanning classes such as oxazolidinone antibacterial, aminoglycoside antibacterial, lipopeptide antibacterial. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for bacterial skin diseases — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Top-rated picks for bacterial skin diseases: 1. Sivextro · 2. Zyvox · 3. Neomycin Sulfate

Top-rated treatments for bacterial skin diseases, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100View →
264/100$1View →
348/100$25View →
4Not yet rated$623View →
5Not yet rated$0View →
6Not yet ratedView →

Full ranking · 6 treatments

sivextro

PrescriptionFDA-sourced

72/100

Sivextro (Tedizolid Phosphate) is a medication used to treat Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases.

(4 data points)
staphylococcal infectionsstreptococcal infectionsskin diseases, bacterial

Price varies

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zyvox

PrescriptionFDA-sourced

64/100

Zyvox (Linezolid) is an oxazolidinone antibacterial used to treat Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases, Bacterial Pneumonia.

(61 data points)
oxazolidinone antibacterialstaphylococcal infectionsstreptococcal infections

Pharmacy pays

From ~$1.43· 2 forms
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neomycin sulfate

Boxed warning

PrescriptionFDA-sourced

48/100

Neomycin Sulfate is an aminoglycoside antibacterial used to treat Escherichia Coli Infections, Hepatic Encephalopathy, Bacterial Skin Diseases.

(124 data points)
aminoglycoside antibacterialescherichia coli infectionshepatic encephalopathy

Pharmacy pays

~$25.36 /30

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dapzura rt

PrescriptionFDA-sourced

New

Dapzura Rt (Daptomycin) is a lipopeptide antibacterial used to treat Bacteremia, Bacterial Skin Diseases.

lipopeptide antibacterialbacteremiaskin diseases, bacterial

Pharmacy pays

From ~$402.54/30· 2 forms
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klaron

PrescriptionFDA-sourced

New

Klaron (Sulfacetamide Sodium) is a sulfonamide antibacterial used to treat Corneal Ulcer, Ear Diseases, Seborrheic Dermatitis, Trachoma.

sulfonamide antibacterialcorneal ulcerear diseases

Pharmacy pays

From ~$0.11· 2 forms
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nuzyra

PrescriptionFDA-sourced

New

Nuzyra (Omadacycline Tosylate) is a medication used to treat Bacterial Infections, Bacterial Skin Diseases, Bacterial Pneumonia.

bacterial infectionsskin diseases, bacterialpneumonia, bacterial

Price varies

View details →

Frequently asked

What treats bacterial skin diseases?
Our catalog lists 6 products that may treat bacterial skin diseases, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is sivextro.
What is the best-rated treatment for bacterial skin diseases?
By our independent recall-safety rating — not an efficacy measure — sivextro ranks highest among the products we list for bacterial skin diseases. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat bacterial skin diseases?
Treatments for bacterial skin diseases span FDA drug classes including oxazolidinone antibacterial, aminoglycoside antibacterial, lipopeptide antibacterial, sulfonamide antibacterial. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.