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Best treatments for pulmonary embolism

10 products may treat pulmonary embolism, spanning FDA drug classes such as direct thrombin inhibitor, low molecular weight heparin, factor xa inhibitor. The current highest-rated option is pradaxa. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 10 drugs we list for pulmonary embolism, 5 are available as lower-cost generics, spanning classes such as direct thrombin inhibitor, low molecular weight heparin, factor xa inhibitor. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for pulmonary embolism — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Top-rated picks for pulmonary embolism: 1. Pradaxa · 2. Activase · 3. Cathflo Activase

Top-rated treatments for pulmonary embolism, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$27View →
270/100View →
370/100View →
470/100$8View →
570/100$1View →
668/100$2View →
768/100$2View →
864/100View →
9Not yet ratedView →
10Not yet ratedView →

Full ranking · 10 treatments

pradaxa

Boxed warning

PrescriptionFDA-sourced

72/100

Pradaxa (Dabigatran Etexilate Mesylate) is a direct thrombin inhibitor used to treat Pulmonary Embolism, Venous Thrombosis.

(6 data points)
direct thrombin inhibitorpulmonary embolismvenous thrombosis

Pharmacy pays

From ~$25.98/30· 3 forms
View details →

activase

PrescriptionFDA-sourced

70/100

Activase (Alteplase) is a medication used to treat Arterial Occlusive Diseases, Intracranial Embolism and Thrombosis, Myocardial Infarction, Pulmonary Embolism.

(5 data points)
arterial occlusive diseasesintracranial embolism and thrombosismyocardial infarction

Price varies

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cathflo activase

PrescriptionFDA-sourced

70/100

Cathflo Activase (Alteplase) is a medication used to treat Arterial Occlusive Diseases, Intracranial Embolism and Thrombosis, Myocardial Infarction, Pulmonary Embolism.

(5 data points)
arterial occlusive diseasesintracranial embolism and thrombosismyocardial infarction

Price varies

View details →
SANOFI AVENTIS US logo

lovenox

PrescriptionFDA-sourced

70/100

Lovenox (Enoxaparin Sodium) is a low molecular weight heparin used to treat Unstable Angina, Myocardial Infarction, Postoperative Complications, Pulmonary Embolism.

(1 data points)
low molecular weight heparinangina, unstablemyocardial infarction

Pharmacy pays

From ~$7.62· 8 forms
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xarelto

Boxed warning

PrescriptionFDA-sourced

70/100

Xarelto (Rivaroxaban) is a factor xa inhibitor used to treat Pulmonary Embolism, Venous Thrombosis.

(2 data points)
factor xa inhibitorpulmonary embolismvenous thrombosis

Pharmacy pays

From ~$0.96· 2 forms
View details →
#3 of 7 in Anti-coagulant

heparin sodium 1,000 units in sodium chloride 0.9% in plastic container

PrescriptionFDA-sourced

68/100

Heparin Sodium 1,000 Units in Sodium Chloride 0.9% in Plastic Container (Heparin Sodium) is an anti-coagulant used to treat Unstable Angina, Cerebral Infarction, Coronary Thrombosis, Myocardial Infarction.

(33 data points)
anti-coagulantunfractionated heparinangina, unstable

Pharmacy pays

From ~$1.14· 4 forms
View details →

Frequently asked

What treats pulmonary embolism?
Our catalog lists 10 products that may treat pulmonary embolism, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is pradaxa.
What is the best-rated treatment for pulmonary embolism?
By our independent recall-safety rating — not an efficacy measure — pradaxa ranks highest among the products we list for pulmonary embolism. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat pulmonary embolism?
Treatments for pulmonary embolism span FDA drug classes including direct thrombin inhibitor, low molecular weight heparin, factor xa inhibitor, anti-coagulant, unfractionated heparin. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.