Best treatments for hiccup
5 products may treat hiccup, spanning FDA drug classes such as non-narcotic antitussive, gamma-aminobutyric acid-ergic agonist. The current highest-rated option is benzonatate. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.
Quick answer: Of the 5 drugs we list for hiccup, all are available as lower-cost generics, spanning classes such as non-narcotic antitussive, gamma-aminobutyric acid-ergic agonist. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for hiccup — so confirm the right choice with your prescriber.
Top-rated picks for hiccup: 1. Benzonatate · 2. Tessalon · 3. Gablofen
| # | Drug | Rating | Type | Form | Class | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Capsule | Non-narcotic Antitussive | Generic | $2 | View → | |
| 2 | 64/100 | Prescription | Capsule | Non-narcotic Antitussive | Generic | $2 | View → | |
| 3 | Not yet rated | Prescription | Injectable | gamma-Aminobutyric Acid-ergic Agonist | Generic | $2 | View → | |
| 4 | Not yet rated | Prescription | Solution | gamma-Aminobutyric Acid-ergic Agonist | Generic | $2 | View → | |
| 5 | Not yet rated | Prescription | Solution | gamma-Aminobutyric Acid-ergic Agonist | Generic | $2 | View → |
Narrow by drug class
Explore the class hubs: gamma-aminobutyric acid-ergic agonist · non-narcotic antitussive
Full ranking · 5 treatments
benzonatate
PrescriptionFDA-sourced
Benzonatate is a non-narcotic antitussive used to treat Cough, Hiccup.
Pharmacy pays
From ~$2.12/30· 2 forms
tessalon
PrescriptionFDA-sourced
Tessalon (Benzonatate) is a non-narcotic antitussive used to treat Cough, Hiccup.
Pharmacy pays
From ~$2.12/30· 2 formsgablofen
Boxed warningPrescriptionFDA-sourced
Gablofen (Baclofen) is a gamma-aminobutyric acid-ergic agonist used to treat Neurogenic Urinary Bladder, Cerebral Palsy, Hiccup, Huntington Disease.
Pharmacy pays
From ~$1.00/30· 7 formsozobax
PrescriptionFDA-sourced
Ozobax (Baclofen) is a gamma-aminobutyric acid-ergic agonist used to treat Neurogenic Urinary Bladder, Cerebral Palsy, Hiccup, Huntington Disease.
Pharmacy pays
From ~$1.00/30· 7 formsozobax ds
PrescriptionFDA-sourced
Ozobax Ds (Baclofen) is a gamma-aminobutyric acid-ergic agonist used to treat Neurogenic Urinary Bladder, Cerebral Palsy, Hiccup, Huntington Disease.
Pharmacy pays
From ~$1.00/30· 7 formsFrequently asked
- What treats hiccup?
- Our catalog lists 5 products that may treat hiccup, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is benzonatate.
- What is the best-rated treatment for hiccup?
- By our independent recall-safety rating — not an efficacy measure — benzonatate ranks highest among the products we list for hiccup. Always consult a professional.
- How are these treatments ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
- What types of drugs treat hiccup?
- Treatments for hiccup span FDA drug classes including non-narcotic antitussive, gamma-aminobutyric acid-ergic agonist. Compare every option side by side, ranked by independent rating, above.
Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.