Best treatments for cystic fibrosis
7 products may treat cystic fibrosis, spanning FDA drug classes such as recombinant human deoxyribonuclease 1, antidote, antidote for acetaminophen overdose. The current highest-rated option is midamor. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.
Quick answer: Of the 7 drugs we list for cystic fibrosis, 3 are available as lower-cost generics, spanning classes such as recombinant human deoxyribonuclease 1, antidote, antidote for acetaminophen overdose. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for cystic fibrosis — so confirm the right choice with your prescriber.
Top-rated picks for cystic fibrosis: 1. Midamor · 2. Pulmozyme · 3. Acetadote
| # | Drug | Rating | Type | Form | Class | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | — | Generic | $6 | View → | |
| 2 | 70/100 | Prescription | Solution | Recombinant Human Deoxyribonuclease 1 | No data | — | View → | |
| 3 | Not yet rated | Prescription | Injectable | Antidote | Generic | $1 | View → | |
| 4 | Not yet rated | Prescription | Tablet | — | Generic | $6 | View → | |
| 5 | Not yet rated | Prescription | Powder | Cystic Fibrosis Transmembrane Conductance Regulator Potentiator | No data | — | View → | |
| 6 | Not yet rated | Prescription | Kit | Nitrogen Binding Agent | No data | — | View → | |
| 7 | Not yet rated | Prescription | Oral pellets | Nitrogen Binding Agent | No data | — | View → |
Narrow by drug class
Explore the class hubs: nitrogen binding agent
Full ranking · 7 treatments
midamor
Boxed warningPrescriptionFDA-sourced
Midamor (Amiloride Hydrochloride) is a medication used to treat Ascites, Cystic Fibrosis, Edema, Heart Failure.
Pharmacy pays
~$6.00 /30
pulmozyme
PrescriptionFDA-sourced
Pulmozyme (Dornase Alfa) is a recombinant human deoxyribonuclease 1 used to treat Bronchitis, Cystic Fibrosis.
Price varies
acetadote
PrescriptionFDA-sourced
Acetadote (Acetylcysteine) is an antidote used to treat Amyloidosis, Bronchiectasis, Bronchitis, Cystic Fibrosis.
Pharmacy pays
From ~$0.97· 2 forms Save up to 38% in classamiloride hydrochloride
PrescriptionFDA-sourced
Amiloride Hydrochloride is a medication used to treat Ascites, Cystic Fibrosis, Edema, Heart Failure.
Pharmacy pays
~$6.00 /30
kalydeco
PrescriptionFDA-sourced
Kalydeco (Ivacaftor) is a cystic fibrosis transmembrane conductance regulator potentiator used to treat Cystic Fibrosis.
Price varies
olpruva
PrescriptionFDA-sourced
Olpruva (Sodium Phenylbutyrate) is a nitrogen binding agent used to treat Sickle Cell Anemia, Cystic Fibrosis, Myeloproliferative Disorders, Beta-Thalassemia.
Price varies
Frequently asked
- What treats cystic fibrosis?
- Our catalog lists 7 products that may treat cystic fibrosis, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is midamor.
- What is the best-rated treatment for cystic fibrosis?
- By our independent recall-safety rating — not an efficacy measure — midamor ranks highest among the products we list for cystic fibrosis. Always consult a professional.
- How are these treatments ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
- What types of drugs treat cystic fibrosis?
- Treatments for cystic fibrosis span FDA drug classes including recombinant human deoxyribonuclease 1, antidote, antidote for acetaminophen overdose, mucolytic, cystic fibrosis transmembrane conductance regulator potentiator. Compare every option side by side, ranked by independent rating, above.
Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.