LINEZOLID vs ZYVOX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Attribute	LINEZOLID	ZYVOX
Rating	70/100	64/100
Pharmacy pays	$1.43 /mL	$1.43 /mL
Type	RX	RX
Active ingredient	LINEZOLID	LINEZOLID
Manufacturer	Macleods Pharms Ltd	Pfizer
Dosage forms	Powder, Injectable, Solution, Suspension, Tablet	Powder, Injectable, Solution, Tablet
Drug class	Oxazolidinone Antibacterial	Oxazolidinone Antibacterial
Boxed warning	None	None
Half-life	about 4.3 to 5.4 hours (roughly 5 hours) in adults	about 4.3 to 5.4 hours (roughly 5 hours) in adults
Treats	Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases	Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

linezolid zyvox

Rating

70/100

64/100

Pharmacy pays

$1.43 /mL

Type

Active ingredient

LINEZOLID

Manufacturer

Macleods Pharms Ltd

Pfizer

Dosage forms

Powder, Injectable, Solution, Suspension, Tablet

Powder, Injectable, Solution, Tablet

Drug class

Oxazolidinone Antibacterial

Boxed warning

None

Half-life

about 4.3 to 5.4 hours (roughly 5 hours) in adults

Treats

Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

Frequently asked questions

Which is better-rated, Linezolid or Zyvox?

By our independent rating, Linezolid scores higher — 3.5 vs 3.2 out of 5 for Zyvox. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Linezolid or Zyvox?

Pharmacies pay about the same to acquire either one — roughly $1.43 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Linezolid and Zyvox?

Both Linezolid and Zyvox share the active ingredient Linezolid.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.