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ONDANSETRON vs ZUPLENZ

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

56/100
New

Pharmacy pays

$0.15 /mL
$0.15 /mL

Type

RX
RX

Active ingredient

ONDANSETRON
ONDANSETRON

Manufacturer

Dosage forms

Injectable, Solution, Tablet, Tablet, orally disintegrating
Film

Drug class

Serotonin-3 Receptor Antagonist
Serotonin-3 Receptor Antagonist

Boxed warning

None
None

Half-life

about 3 to 5 hours (roughly 4 hours) in healthy adults
about 3 to 5 hours (roughly 4 hours) in healthy adults

Treats

Alcoholism
Alcoholism

Frequently asked questions

Which is cheaper, Ondansetron or Zuplenz?

Pharmacies pay about the same to acquire either one — roughly $0.15 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Ondansetron and Zuplenz?

Both Ondansetron and Zuplenz share the active ingredient Ondansetron.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.