ZITUVIMET vs ZITUVIMET XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ZITUVIMET	ZITUVIMET XR
Rating	New	New
Pharmacy pays	~$0.74 /30	~$0.74 /30
Type	RX	RX
Active ingredient	METFORMIN HYDROCHLORIDE AND SITAGLIPTIN	METFORMIN HYDROCHLORIDE AND SITAGLIPTIN
Manufacturer	Zydus Lifesciences	Zydus Lifesciences
Dosage forms	Tablet	Tablet, extended release
Drug class	—	—
Boxed warning	Boxed warning	Boxed warning
Half-life	about 12.4 hours (apparent terminal half-life after a single 100 mg oral dose in healthy volunteers)	about 12.4 hours (apparent terminal half-life after a single 100 mg oral dose in healthy volunteers)

zituvimet zituvimet xr

Rating

New

Pharmacy pays

~$0.74 /30

Type

Active ingredient

METFORMIN HYDROCHLORIDE AND SITAGLIPTIN

Manufacturer

Zydus Lifesciences

Dosage forms

Tablet

Tablet, extended release

Drug class

—

Boxed warning

Half-life

about 12.4 hours (apparent terminal half-life after a single 100 mg oral dose in healthy volunteers)

Frequently asked questions

Which is cheaper, Zituvimet or Zituvimet XR?

Pharmacies pay about the same to acquire either one — roughly $0.74 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Zituvimet and Zituvimet XR?

Both Zituvimet and Zituvimet XR share the active ingredient Metformin Hydrochloride and Sitagliptin.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.