ZETIA vs ZOCOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. ZETIA and ZOCOR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ZETIA	ZOCOR
Rating	72/100	72/100
Pharmacy pays	~$2.17 /30	~$0.94 /30
Type	RX	RX
Active ingredient	EZETIMIBE	SIMVASTATIN
Manufacturer	Organon	Organon
Dosage forms	Tablet	Tablet
Drug class	Dietary Cholesterol Absorption Inhibitor	Hmg-Coa Reductase Inhibitor
Boxed warning	None	None
Half-life	about 22 hours	about 2 hours (short) in typical adults
Treats	Hypercholesterolemia, Hyperlipoproteinemia Type II, Familial Combined Hyperlipidemia	Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

zetia zocor

Rating

72/100

Pharmacy pays

~$2.17 /30

~$0.94 /30

Type

Active ingredient

EZETIMIBE

SIMVASTATIN

Manufacturer

Organon

Dosage forms

Tablet

Drug class

Dietary Cholesterol Absorption Inhibitor

Hmg-Coa Reductase Inhibitor

Boxed warning

None

Half-life

about 22 hours

about 2 hours (short) in typical adults

Treats

Hypercholesterolemia, Hyperlipoproteinemia Type II, Familial Combined Hyperlipidemia

Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

Frequently asked questions

Which is better-rated, Zetia or Zocor?

Zetia and Zocor are tied at 3.6 out of 5 by our independent rating.

Which is cheaper, Zetia or Zocor?

Zocor costs pharmacies less to acquire — about $0.94 vs $2.17 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Zetia and Zocor?

Zetia contains Ezetimibe, while Zocor contains Simvastatin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.