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LISINOPRIL AND HYDROCHLOROTHIAZIDE vs ZESTORETIC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$0.91 /30
~$0.91 /30

Type

RX
RX

Active ingredient

HYDROCHLOROTHIAZIDE AND LISINOPRIL
HYDROCHLOROTHIAZIDE AND LISINOPRIL

Dosage forms

Tablet
Tablet

Drug class

Boxed warning

Half-life

about 6 to 15 hours (the label reports a range, not a single number)
about 6 to 15 hours (the label reports a range, not a single number)

Frequently asked questions

Which is cheaper, Lisinopril and Hydrochlorothiazide or Zestoretic?

Pharmacies pay about the same to acquire either one — roughly $0.91 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Lisinopril and Hydrochlorothiazide and Zestoretic?

Both Lisinopril and Hydrochlorothiazide and Zestoretic share the active ingredient Hydrochlorothiazide and Lisinopril.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.