XYZAL vs XYZAL ALLERGY 24HR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	XYZAL	XYZAL ALLERGY 24HR
Rating	New	New
Pharmacy pays	$0.06 /mL	$0.06 /mL
Type	RX	OTC
Active ingredient	LEVOCETIRIZINE DIHYDROCHLORIDE	LEVOCETIRIZINE DIHYDROCHLORIDE
Manufacturer	Chattem Sanofi	Chattem Sanofi
Dosage forms	Solution, Tablet	Tablet
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Treats	Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria	Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

xyzal xyzal allergy 24hr

Rating

New

Pharmacy pays

$0.06 /mL

Type

OTC

Active ingredient

LEVOCETIRIZINE DIHYDROCHLORIDE

Manufacturer

Chattem Sanofi

Dosage forms

Solution, Tablet

Tablet

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Treats

Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

Which is cheaper, Xyzal or Xyzal Allergy 24hr?

Pharmacies pay about the same to acquire either one — roughly $0.06 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Xyzal and Xyzal Allergy 24hr?

Both Xyzal and Xyzal Allergy 24hr share the active ingredient Levocetirizine Dihydrochloride, but Xyzal is sold as RX and Xyzal Allergy 24hr as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.