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XOPENEX vs XOPENEX HFA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. XOPENEX and XOPENEX HFA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
58/100

Pharmacy pays

$0.27 /mL
$0.27 /mL

Type

RX
RX

Active ingredient

LEVALBUTEROL HYDROCHLORIDE
LEVALBUTEROL TARTRATE

Manufacturer

Dosage forms

Solution
Spray/Inhaler, metered

Drug class

Beta2-Adrenergic Agonist
Beta2-Adrenergic Agonist

Boxed warning

None
None

Treats

Bronchial Spasm
Bronchial Spasm

Frequently asked questions

Which is better-rated, Xopenex or Xopenex Hfa?

By our independent rating, Xopenex scores higher — 3.6 vs 2.9 out of 5 for Xopenex Hfa. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Xopenex or Xopenex Hfa?

Pharmacies pay about the same to acquire either one — roughly $0.27 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Xopenex and Xopenex Hfa?

Xopenex contains Levalbuterol Hydrochloride, while Xopenex Hfa contains Levalbuterol Tartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.