VOLTAREN-XR vs VYSCOXA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. VOLTAREN-XR and VYSCOXA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	VOLTAREN-XR	VYSCOXA
Rating	70/100	New
Pharmacy pays	$0.36 /mL	~$2.45 /30
Type	RX	RX
Active ingredient	DICLOFENAC SODIUM	CELECOXIB
Manufacturer	Novartis	Carwin Pharm Assoc
Dosage forms	Tablet, extended release	Suspension
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)	about 11 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea	Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

voltaren-xr vyscoxa

Rating

70/100

New

Pharmacy pays

$0.36 /mL

~$2.45 /30

Type

Active ingredient

DICLOFENAC SODIUM

CELECOXIB

Manufacturer

Novartis

Carwin Pharm Assoc

Dosage forms

Tablet, extended release

Suspension

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

about 11 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

Frequently asked questions

What is the difference between Voltaren-XR and Vyscoxa?

Voltaren-XR contains Diclofenac Sodium, while Vyscoxa contains Celecoxib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.