ULTRAM vs WESTADONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. ULTRAM and WESTADONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ULTRAM	WESTADONE
Rating	70/100	68/100
Pharmacy pays	~$0.72 /30	$0.18 /mL
Type	RX	RX
Active ingredient	TRAMADOL HYDROCHLORIDE	METHADONE HYDROCHLORIDE
Manufacturer	Janssen Pharms	Sandoz
Dosage forms	Tablet	Tablet, effervescent
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)	about 8 to 59 hours (terminal/elimination half-life; a very wide range)
Treats	Pain	Opioid-Related Disorders, Intractable Pain

ultram westadone

Rating

70/100

68/100

Pharmacy pays

~$0.72 /30

$0.18 /mL

Type

Active ingredient

TRAMADOL HYDROCHLORIDE

METHADONE HYDROCHLORIDE

Manufacturer

Janssen Pharms

Sandoz

Dosage forms

Tablet

Tablet, effervescent

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Pain

Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is better-rated, Ultram or Westadone?

By our independent rating, Ultram scores higher — 3.5 vs 3.4 out of 5 for Westadone. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Ultram and Westadone?

Ultram contains Tramadol Hydrochloride, while Westadone contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.