ULESFIA vs VALTREX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. ULESFIA and VALTREX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ULESFIA	VALTREX
Rating	70/100	70/100
Pharmacy pays	—	~$7.02 /30
Type	RX	RX
Active ingredient	BENZYL ALCOHOL	VALACYCLOVIR HYDROCHLORIDE
Manufacturer	Shionogi	Glaxosmithkline
Dosage forms	Topical	Tablet
Drug class	—	Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor
Boxed warning	None	None
Treats	Herpes Labialis, Lice Infestations	Chickenpox, Herpes Genitalis, Herpes Labialis

ulesfia valtrex

Rating

70/100

Pharmacy pays

—

~$7.02 /30

Type

Active ingredient

BENZYL ALCOHOL

VALACYCLOVIR HYDROCHLORIDE

Manufacturer

Shionogi

Glaxosmithkline

Dosage forms

Topical

Tablet

Drug class

—

Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor

Boxed warning

None

Treats

Herpes Labialis, Lice Infestations

Chickenpox, Herpes Genitalis, Herpes Labialis

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Frequently asked questions

Which is better-rated, Ulesfia or Valtrex?

Ulesfia and Valtrex are tied at 3.5 out of 5 by our independent rating.

What is the difference between Ulesfia and Valtrex?

Ulesfia contains Benzyl Alcohol, while Valtrex contains Valacyclovir Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.