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TROSPIUM CHLORIDE vs VESICARE LS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. TROSPIUM CHLORIDE and VESICARE LS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

trospium chloridevesicare ls

Rating

72/100
72/100

Pharmacy pays

~$7.08 /30
~$5.40 /30

Type

RX
RX

Active ingredient

TROSPIUM CHLORIDE
SOLIFENACIN SUCCINATE

Manufacturer

Granules
Astellas

Dosage forms

Capsule, extended release, Tablet
Suspension

Drug class

Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonist

Boxed warning

None
None

Half-life

—
about 45 to 68 hours

Treats

Overactive Urinary Bladder, Urge Urinary Incontinence
Overactive Urinary Bladder, Urge Urinary Incontinence

Frequently asked questions

Which is better-rated, Trospium Chloride or Vesicare Ls?

Trospium Chloride and Vesicare Ls are tied at 3.6 out of 5 by our independent rating.

Which is cheaper, Trospium Chloride or Vesicare Ls?

Vesicare Ls costs pharmacies less to acquire — about $5.40 vs $7.08 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Trospium Chloride and Vesicare Ls?

Trospium Chloride contains Trospium Chloride, while Vesicare Ls contains Solifenacin Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.