TRINTELLIX vs VIIBRYD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. TRINTELLIX and VIIBRYD are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	TRINTELLIX	VIIBRYD
Rating	New	72/100
Pharmacy pays	—	~$29.59 /30
Type	RX	RX
Active ingredient	VORTIOXETINE HYDROBROMIDE	VILAZODONE HYDROCHLORIDE
Manufacturer	Takeda Pharms USA	Abbvie
Dosage forms	Tablet	Tablet
Drug class	—	—
Boxed warning	Boxed warning	Boxed warning
Treats	Major Depressive Disorder	Major Depressive Disorder

trintellix viibryd

Rating

New

72/100

Pharmacy pays

—

~$29.59 /30

Type

Active ingredient

VORTIOXETINE HYDROBROMIDE

VILAZODONE HYDROCHLORIDE

Manufacturer

Takeda Pharms USA

Abbvie

Dosage forms

Tablet

Drug class

—

Boxed warning

Treats

Major Depressive Disorder

Frequently asked questions

What is the difference between Trintellix and Viibryd?

Trintellix contains Vortioxetine Hydrobromide, while Viibryd contains Vilazodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.