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TRAMADOL HYDROCHLORIDE vs ULTRAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Rating

New
70/100

Pharmacy pays

~$0.72 /30
~$0.72 /30

Type

RX
RX

Active ingredient

TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE

Dosage forms

Tablet, Tablet, extended release
Tablet

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)
about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Pain
Pain

Frequently asked questions

Which is cheaper, Tramadol Hydrochloride or Ultram?

Pharmacies pay about the same to acquire either one — roughly $0.72 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Tramadol Hydrochloride and Ultram?

Both Tramadol Hydrochloride and Ultram share the active ingredient Tramadol Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.