TOSYMRA vs ZECUITY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. TOSYMRA and ZECUITY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	TOSYMRA	ZECUITY
Rating	New	New
Pharmacy pays	~$481.89 /30	~$481.89 /30
Type	RX	RX
Active ingredient	SUMATRIPTAN	SUMATRIPTAN SUCCINATE
Manufacturer	Tonix Meds	Teva Branded Pharm
Dosage forms	Spray/Inhaler	System
Drug class	Serotonin-1b and Serotonin-1d Receptor Agonist	Serotonin-1b and Serotonin-1d Receptor Agonist
Boxed warning	None	None
Half-life	about 2 hours (terminal elimination half-life 115 ± 19 minutes)	about 2 hours (terminal elimination half-life 115 ± 19 minutes)
Treats	Cluster Headache, Migraine Disorders	Cluster Headache, Migraine Disorders

tosymra zecuity

Rating

New

Pharmacy pays

~$481.89 /30

Type

Active ingredient

SUMATRIPTAN

SUMATRIPTAN SUCCINATE

Manufacturer

Tonix Meds

Teva Branded Pharm

Dosage forms

Spray/Inhaler

System

Drug class

Serotonin-1b and Serotonin-1d Receptor Agonist

Boxed warning

None

Half-life

about 2 hours (terminal elimination half-life 115 ± 19 minutes)

Treats

Cluster Headache, Migraine Disorders

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Frequently asked questions

Which is cheaper, Tosymra or Zecuity?

Pharmacies pay about the same to acquire either one — roughly $481.89 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Tosymra and Zecuity?

Tosymra contains Sumatriptan, while Zecuity contains Sumatriptan Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.