TOFACITINIB CITRATE vs UPADACITINIB

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. TOFACITINIB CITRATE and UPADACITINIB are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	TOFACITINIB CITRATE	UPADACITINIB
Rating	New	68/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	TOFACITINIB CITRATE	UPADACITINIB
Manufacturer	Somerset Theraps LLC	Sandoz
Dosage forms	Tablet, extended release	Tablet, extended release, Tablet
Drug class	Janus Kinase Inhibitor	Janus Kinase Inhibitor
Boxed warning	Boxed warning	None
Half-life	—	about 8 to 14 hours (mean terminal elimination half-life)
Treats	Rheumatoid Arthritis	Rheumatoid Arthritis

tofacitinib citrate upadacitinib

Rating

New

68/100

Pharmacy pays

—

Type

Active ingredient

TOFACITINIB CITRATE

UPADACITINIB

Manufacturer

Somerset Theraps LLC

Sandoz

Dosage forms

Tablet, extended release

Tablet, extended release, Tablet

Drug class

Janus Kinase Inhibitor

Boxed warning

None

Half-life

—

about 8 to 14 hours (mean terminal elimination half-life)

Treats

Rheumatoid Arthritis

Frequently asked questions

What is the difference between Tofacitinib Citrate and Upadacitinib?

Tofacitinib Citrate contains Tofacitinib Citrate, while Upadacitinib contains Upadacitinib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.