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TIZANIDINE HYDROCHLORIDE vs ZANAFLEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$1.00 /30
~$1.00 /30

Type

RX
RX

Active ingredient

TIZANIDINE HYDROCHLORIDE
TIZANIDINE HYDROCHLORIDE

Dosage forms

Capsule, Tablet
Capsule, Tablet

Drug class

Central Alpha-2 Adrenergic Agonist
Central Alpha-2 Adrenergic Agonist

Boxed warning

None
None

Half-life

about 2.5 hours
about 2.5 hours

Treats

Muscle Cramp, Muscle Rigidity, Muscle Spasticity
Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Frequently asked questions

Which is cheaper, Tizanidine Hydrochloride or Zanaflex?

Pharmacies pay about the same to acquire either one — roughly $1.00 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Tizanidine Hydrochloride and Zanaflex?

Both Tizanidine Hydrochloride and Zanaflex share the active ingredient Tizanidine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.