TIMOPTIC-XE vs TRANDATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. TIMOPTIC-XE and TRANDATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	TIMOPTIC-XE	TRANDATE
Rating	New	New
Pharmacy pays	$1.06 /mL	~$4.36 /30
Type	RX	RX
Active ingredient	TIMOLOL MALEATE	LABETALOL HYDROCHLORIDE
Manufacturer	Bausch and Lomb	Sebela Ireland Ltd
Dosage forms	Solution	Tablet
Drug class	Beta-Adrenergic Blocker	Beta-Adrenergic Blocker
Boxed warning	None	None
Half-life	—	about 6 to 8 hours after an oral dose (about 5.5 hours after an intravenous dose)
Treats	Angina Pectoris, Open-Angle Glaucoma, Heart Failure	Angina Pectoris, Heart Failure, Malignant Hypertension

timoptic-xe trandate

Rating

New

Pharmacy pays

$1.06 /mL

~$4.36 /30

Type

Active ingredient

TIMOLOL MALEATE

LABETALOL HYDROCHLORIDE

Manufacturer

Bausch and Lomb

Sebela Ireland Ltd

Dosage forms

Solution

Tablet

Drug class

Beta-Adrenergic Blocker

Boxed warning

None

Half-life

—

about 6 to 8 hours after an oral dose (about 5.5 hours after an intravenous dose)

Treats

Angina Pectoris, Open-Angle Glaucoma, Heart Failure

Angina Pectoris, Heart Failure, Malignant Hypertension

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Frequently asked questions

What is the difference between Timoptic-Xe and Trandate?

Timoptic-Xe contains Timolol Maleate, while Trandate contains Labetalol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.