TEFLARO vs ZYVOX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. TEFLARO and ZYVOX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	TEFLARO	ZYVOX
Rating	72/100	64/100
Pharmacy pays	—	$1.43 /mL
Type	RX	RX
Active ingredient	CEFTAROLINE FOSAMIL	LINEZOLID
Manufacturer	Abbvie	Pfizer
Dosage forms	Powder	Powder, Injectable, Solution, Tablet
Drug class	—	Oxazolidinone Antibacterial
Boxed warning	None	None
Half-life	—	about 4.3 to 5.4 hours (roughly 5 hours) in adults
Treats	Escherichia Coli Infections, Klebsiella Infections, Pneumonia	Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

teflaro zyvox

Rating

72/100

64/100

Pharmacy pays

—

$1.43 /mL

Type

Active ingredient

CEFTAROLINE FOSAMIL

LINEZOLID

Manufacturer

Abbvie

Pfizer

Dosage forms

Powder

Powder, Injectable, Solution, Tablet

Drug class

—

Oxazolidinone Antibacterial

Boxed warning

None

Half-life

—

about 4.3 to 5.4 hours (roughly 5 hours) in adults

Treats

Escherichia Coli Infections, Klebsiella Infections, Pneumonia

Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

Frequently asked questions

Which is better-rated, Teflaro or Zyvox?

By our independent rating, Teflaro scores higher — 3.6 vs 3.2 out of 5 for Zyvox. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Teflaro and Zyvox?

Teflaro contains Ceftaroline Fosamil, while Zyvox contains Linezolid — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.