TECENTRIQ vs ZEPZELCA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. TECENTRIQ and ZEPZELCA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	TECENTRIQ	ZEPZELCA
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ATEZOLIZUMAB	LURBINECTEDIN
Manufacturer	Genentech Inc	Jazz
Dosage forms	Injectable	Injectable
Drug class	—	—
Boxed warning	None	None
Treats	Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Hepatocellular Carcinoma	Small Cell Lung Carcinoma

tecentriq zepzelca

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

ATEZOLIZUMAB

LURBINECTEDIN

Manufacturer

Genentech Inc

Jazz

Dosage forms

Injectable

Drug class

—

Boxed warning

None

Treats

Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Hepatocellular Carcinoma

Small Cell Lung Carcinoma

Frequently asked questions

What is the difference between Tecentriq and Zepzelca?

Tecentriq contains Atezolizumab, while Zepzelca contains Lurbinectedin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.