SYNTHROID vs THYROGEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. SYNTHROID and THYROGEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SYNTHROID	THYROGEN
Rating	68/100	72/100
Pharmacy pays	~$1.79 /30	—
Type	RX	RX
Active ingredient	LEVOTHYROXINE SODIUM	THYROTROPIN ALFA
Manufacturer	Abbvie	Genzyme
Dosage forms	Tablet	Injectable
Drug class	L-Thyroxine	Thyroid Stimulating Hormone
Boxed warning	Boxed warning	None
Half-life	about 6 to 7 days in adults with normal thyroid function	—
Treats	Goiter, Myxedema, Thyroid Neoplasms	Thyroid Neoplasms

synthroid thyrogen

Rating

68/100

72/100

Pharmacy pays

~$1.79 /30

—

Type

Active ingredient

LEVOTHYROXINE SODIUM

THYROTROPIN ALFA

Manufacturer

Abbvie

Genzyme

Dosage forms

Tablet

Injectable

Drug class

L-Thyroxine

Thyroid Stimulating Hormone

Boxed warning

None

Half-life

about 6 to 7 days in adults with normal thyroid function

—

Treats

Goiter, Myxedema, Thyroid Neoplasms

Thyroid Neoplasms

Frequently asked questions

Which is better-rated, Synthroid or Thyrogen?

By our independent rating, Thyrogen scores higher — 3.6 vs 3.4 out of 5 for Synthroid. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Synthroid and Thyrogen?

Synthroid contains Levothyroxine Sodium, while Thyrogen contains Thyrotropin Alfa — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.