SYMPROIC vs ZURNAI (AUTOINJECTOR)

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. SYMPROIC and ZURNAI (AUTOINJECTOR) are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SYMPROIC	ZURNAI (AUTOINJECTOR)
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	NALDEMEDINE TOSYLATE	NALMEFENE HYDROCHLORIDE
Manufacturer	Bdsi	Knoa Pharma
Dosage forms	Tablet	Injectable
Drug class	Opioid Antagonist	Opioid Antagonist
Boxed warning	None	None
Treats	Constipation	Opioid-Related Disorders, Respiration Disorders, Drug Overdose

symproic zurnai (autoinjector)

Rating

New

Pharmacy pays

—

Type

Active ingredient

NALDEMEDINE TOSYLATE

NALMEFENE HYDROCHLORIDE

Manufacturer

Bdsi

Knoa Pharma

Dosage forms

Tablet

Injectable

Drug class

Opioid Antagonist

Boxed warning

None

Treats

Constipation

Opioid-Related Disorders, Respiration Disorders, Drug Overdose

Frequently asked questions

What is the difference between Symproic and Zurnai (Autoinjector)?

Symproic contains Naldemedine Tosylate, while Zurnai (Autoinjector) contains Nalmefene Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.