SYMPAZAN vs VALRELEASE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. SYMPAZAN and VALRELEASE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SYMPAZAN	VALRELEASE
Rating	New	New
Pharmacy pays	~$7.72 /30	~$0.87 /30
Type	RX	RX
Active ingredient	CLOBAZAM	DIAZEPAM
Manufacturer	Assertio Speclty	Roche
Dosage forms	Film	Capsule, extended release
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	None
Half-life	—	about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age
Treats	Seizures, Lennox Gastaut Syndrome	Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

sympazan valrelease

Rating

New

Pharmacy pays

~$7.72 /30

~$0.87 /30

Type

Active ingredient

CLOBAZAM

DIAZEPAM

Manufacturer

Assertio Speclty

Roche

Dosage forms

Film

Capsule, extended release

Drug class

Benzodiazepine

Boxed warning

None

Half-life

—

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

Treats

Seizures, Lennox Gastaut Syndrome

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

Frequently asked questions

Which is cheaper, Sympazan or Valrelease?

Valrelease costs pharmacies less to acquire — about $0.87 vs $7.72 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Sympazan and Valrelease?

Sympazan contains Clobazam, while Valrelease contains Diazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.