SURMONTIL vs ZONALON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. SURMONTIL and ZONALON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SURMONTIL	ZONALON
Rating	New	66/100
Pharmacy pays	—	~$4.84 /30
Type	RX	RX
Active ingredient	TRIMIPRAMINE MALEATE	DOXEPIN HYDROCHLORIDE
Manufacturer	Teva Womens	Mylan
Dosage forms	Capsule	Topical
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	None	None
Half-life	—	about 8 to 24 hours (average about 17 hours)
Treats	Depressive Disorder	Anxiety Disorders, Depressive Disorder, Atopic Dermatitis

surmontil zonalon

Rating

New

66/100

Pharmacy pays

—

~$4.84 /30

Type

Active ingredient

TRIMIPRAMINE MALEATE

DOXEPIN HYDROCHLORIDE

Manufacturer

Teva Womens

Mylan

Dosage forms

Capsule

Topical

Drug class

Tricyclic Antidepressant

Boxed warning

None

Half-life

—

about 8 to 24 hours (average about 17 hours)

Treats

Depressive Disorder

Anxiety Disorders, Depressive Disorder, Atopic Dermatitis

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Frequently asked questions

What is the difference between Surmontil and Zonalon?

Surmontil contains Trimipramine Maleate, while Zonalon contains Doxepin Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.