SPRYCEL vs TEPMETKO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. SPRYCEL and TEPMETKO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SPRYCEL	TEPMETKO
Rating	72/100	70/100
Pharmacy pays	~$839.19 /30	—
Type	RX	RX
Active ingredient	DASATINIB	TEPOTINIB HYDROCHLORIDE
Manufacturer	Bristol Myers Squibb	Emd Serono
Dosage forms	Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Lymphoid Leukemia, Myeloid Leukemia	—

sprycel tepmetko

Rating

72/100

70/100

Pharmacy pays

~$839.19 /30

—

Type

Active ingredient

DASATINIB

TEPOTINIB HYDROCHLORIDE

Manufacturer

Bristol Myers Squibb

Emd Serono

Dosage forms

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Lymphoid Leukemia, Myeloid Leukemia

—

Frequently asked questions

Which is better-rated, Sprycel or Tepmetko?

By our independent rating, Sprycel scores higher — 3.6 vs 3.5 out of 5 for Tepmetko. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Sprycel and Tepmetko?

Sprycel contains Dasatinib, while Tepmetko contains Tepotinib Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.