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SORINE vs TIKOSYN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. SORINE and TIKOSYN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
60/100

Pharmacy pays

~$2.96 /30
~$5.80 /30

Type

RX
RX

Active ingredient

SOTALOL HYDROCHLORIDE
DOFETILIDE

Dosage forms

Tablet
Capsule

Drug class

Antiarrhythmic
Antiarrhythmic

Half-life

about 12 hours (the label gives a mean elimination half-life of 12 hours)

Treats

Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia
Atrial Fibrillation, Atrial Flutter

Frequently asked questions

Which is cheaper, Sorine or Tikosyn?

Sorine costs pharmacies less to acquire — about $2.96 vs $5.80 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Sorine and Tikosyn?

Sorine contains Sotalol Hydrochloride, while Tikosyn contains Dofetilide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.