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SITAGLIPTIN vs TRADJENTA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. SITAGLIPTIN and TRADJENTA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
72/100

Pharmacy pays

~$110.51 /30

Type

RX
RX

Active ingredient

SITAGLIPTIN PHOSPHATE
LINAGLIPTIN

Dosage forms

Tablet
Tablet

Drug class

Dipeptidyl Peptidase 4 Inhibitor
Dipeptidyl Peptidase 4 Inhibitor

Boxed warning

None
None

Half-life

about 12.4 hours (apparent terminal half-life after a single 100 mg oral dose in healthy volunteers)
about 200 hours — the terminal (elimination) half-life at steady state, per the label

Treats

Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus

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Frequently asked questions

What is the difference between Sitagliptin and Tradjenta?

Sitagliptin contains Sitagliptin Phosphate, while Tradjenta contains Linagliptin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.