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SEROQUEL vs SEROQUEL XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$2.62 /30
~$2.62 /30

Type

RX
RX

Active ingredient

QUETIAPINE FUMARATE
QUETIAPINE FUMARATE

Dosage forms

Tablet
Tablet, extended release

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Boxed warning

Half-life

about 6 hours
about 6 hours

Treats

Autistic Disorder, Bipolar Disorder, Major Depressive Disorder
Autistic Disorder, Bipolar Disorder, Major Depressive Disorder

Frequently asked questions

Which is cheaper, Seroquel or Seroquel XR?

Pharmacies pay about the same to acquire either one — roughly $2.62 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Seroquel and Seroquel XR?

Both Seroquel and Seroquel XR share the active ingredient Quetiapine Fumarate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.