RUFEN vs XIFYRM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. RUFEN and XIFYRM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	RUFEN	XIFYRM
Rating	70/100	70/100
Pharmacy pays	$0.04 /mL	~$0.56 /30
Type	RX	RX
Active ingredient	IBUPROFEN	MELOXICAM
Manufacturer	Basf	Azurity
Dosage forms	Tablet	Injectable
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	about 1.8 to 2.0 hours	about 15 to 20 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Rheumatoid Arthritis, Osteoarthritis

rufen xifyrm

Rating

70/100

Pharmacy pays

$0.04 /mL

~$0.56 /30

Type

Active ingredient

IBUPROFEN

MELOXICAM

Manufacturer

Basf

Azurity

Dosage forms

Tablet

Injectable

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

about 1.8 to 2.0 hours

about 15 to 20 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Rheumatoid Arthritis, Osteoarthritis

Frequently asked questions

Which is better-rated, Rufen or Xifyrm?

Rufen and Xifyrm are tied at 3.5 out of 5 by our independent rating.

What is the difference between Rufen and Xifyrm?

Rufen contains Ibuprofen, while Xifyrm contains Meloxicam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.