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ROFLUMILAST vs ZORYVE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

66/100
New

Pharmacy pays

~$10.09 /30
~$10.09 /30

Type

RX
RX

Active ingredient

ROFLUMILAST
ROFLUMILAST

Manufacturer

Dosage forms

Tablet
Spray/Inhaler, Topical

Drug class

Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 Inhibitor

Boxed warning

None
None

Treats

Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease

Frequently asked questions

Which is cheaper, Roflumilast or Zoryve?

Pharmacies pay about the same to acquire either one — roughly $10.09 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Roflumilast and Zoryve?

Both Roflumilast and Zoryve share the active ingredient Roflumilast.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.