RHOFADE vs UPNEEQ

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Attribute	RHOFADE	UPNEEQ
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	OXYMETAZOLINE HYDROCHLORIDE	OXYMETAZOLINE HYDROCHLORIDE
Manufacturer	Mayne Pharma	Rvl Pharms
Dosage forms	Topical	Drops
Drug class	Vasoconstrictor	Vasoconstrictor
Boxed warning	None	None
Treats	Common Cold, Conjunctivitis, Rhinitis	Common Cold, Conjunctivitis, Rhinitis

rhofade upneeq

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

OXYMETAZOLINE HYDROCHLORIDE

Manufacturer

Mayne Pharma

Rvl Pharms

Dosage forms

Topical

Drops

Drug class

Vasoconstrictor

Boxed warning

None

Treats

Common Cold, Conjunctivitis, Rhinitis

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Frequently asked questions

What is the difference between Rhofade and Upneeq?

Both Rhofade and Upneeq share the active ingredient Oxymetazoline Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.