REZENOPY vs SYMPROIC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. REZENOPY and SYMPROIC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	REZENOPY	SYMPROIC
Rating	New	New
Pharmacy pays	$4.41 /mL	—
Type	RX	RX
Active ingredient	NALOXONE HYDROCHLORIDE	NALDEMEDINE TOSYLATE
Manufacturer	Scienture	Bdsi
Dosage forms	Spray/Inhaler	Tablet
Drug class	Opioid Antagonist	Opioid Antagonist
Boxed warning	None	None
Half-life	30 to 81 minutes (mean 64 ± 12 minutes)	—
Treats	Opioid-Related Disorders, Respiration Disorders, Septic Shock	Constipation

rezenopy symproic

Rating

New

Pharmacy pays

$4.41 /mL

—

Type

Active ingredient

NALOXONE HYDROCHLORIDE

NALDEMEDINE TOSYLATE

Manufacturer

Scienture

Bdsi

Dosage forms

Spray/Inhaler

Tablet

Drug class

Opioid Antagonist

Boxed warning

None

Half-life

30 to 81 minutes (mean 64 ± 12 minutes)

—

Treats

Opioid-Related Disorders, Respiration Disorders, Septic Shock

Constipation

Frequently asked questions

What is the difference between Rezenopy and Symproic?

Rezenopy contains Naloxone Hydrochloride, while Symproic contains Naldemedine Tosylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.