REXULTI vs UZEDY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. REXULTI and UZEDY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	REXULTI	UZEDY
Rating	New	56/100
Pharmacy pays	—	~$2.07 /30
Type	RX	RX
Active ingredient	BREXPIPRAZOLE	RISPERIDONE
Manufacturer	Otsuka	Teva
Dosage forms	Tablet, Kit	Injectable
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)
Treats	Major Depressive Disorder, Schizophrenia	Autistic Disorder, Bipolar Disorder, Dementia

rexulti uzedy

Rating

New

56/100

Pharmacy pays

—

~$2.07 /30

Type

Active ingredient

BREXPIPRAZOLE

RISPERIDONE

Manufacturer

Otsuka

Teva

Dosage forms

Tablet, Kit

Injectable

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

—

about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)

Treats

Major Depressive Disorder, Schizophrenia

Autistic Disorder, Bipolar Disorder, Dementia

Frequently asked questions

What is the difference between Rexulti and Uzedy?

Rexulti contains Brexpiprazole, while Uzedy contains Risperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.