RETIN-A vs TENORETIC 100

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. RETIN-A and TENORETIC 100 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	RETIN-A	TENORETIC 100
Rating	74/100	New
Pharmacy pays	$1.05 /g	~$0.76 /30
Type	RX	RX
Active ingredient	TRETINOIN	ATENOLOL AND CHLORTHALIDONE
Manufacturer	Valeant Pharm Intl	Twi Pharms
Dosage forms	Topical	Tablet
Drug class	Retinoid	—
Boxed warning	None	None
Half-life	—	about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)
Treats	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia	—

retin-a tenoretic 100

Rating

74/100

New

Pharmacy pays

$1.05 /g

~$0.76 /30

Type

Active ingredient

TRETINOIN

ATENOLOL AND CHLORTHALIDONE

Manufacturer

Valeant Pharm Intl

Twi Pharms

Dosage forms

Topical

Tablet

Drug class

Retinoid

—

Boxed warning

None

Half-life

—

about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)

Treats

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

—

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Frequently asked questions

What is the difference between Retin-A and Tenoretic 100?

Retin-A contains Tretinoin, while Tenoretic 100 contains Atenolol and Chlorthalidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.