RETIN-A vs RIMSO-50

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. RETIN-A and RIMSO-50 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	RETIN-A	RIMSO-50
Rating	74/100	70/100
Pharmacy pays	$1.05 /g	—
Type	RX	RX
Active ingredient	TRETINOIN	DIMETHYL SULFOXIDE
Manufacturer	Valeant Pharm Intl	Mylan Institutional
Dosage forms	Topical	Irrigant
Drug class	Retinoid	—
Boxed warning	None	None
Treats	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia	—

retin-a rimso-50

Rating

74/100

70/100

Pharmacy pays

$1.05 /g

—

Type

Active ingredient

TRETINOIN

DIMETHYL SULFOXIDE

Manufacturer

Valeant Pharm Intl

Mylan Institutional

Dosage forms

Topical

Irrigant

Drug class

Retinoid

—

Boxed warning

None

Treats

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

—

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Frequently asked questions

Which is better-rated, Retin-A or Rimso-50?

By our independent rating, Retin-A scores higher — 3.7 vs 3.5 out of 5 for Rimso-50. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Retin-A and Rimso-50?

Retin-A contains Tretinoin, while Rimso-50 contains Dimethyl Sulfoxide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.